Depression affects people in different ways, and for some individuals, symptoms may persist even after several therapeutic approaches have been tried. When depression does not improve despite multiple antidepressant medications being taken at appropriate doses and durations, it may be described as treatment-resistant depression (TRD). At Camberwell Specialists, Esketamine treatment in Melbourne is one of the clinical options that may be considered for eligible adults after a thorough psychiatric assessment.
Esketamine treatment for depression is provided only in a controlled healthcare environment and may be discussed when other treatment avenues have not resulted in adequate improvement. Decisions about whether Esketamine treatment may be suitable are made collaboratively between the individual and practitioner based on clinical history and personal circumstances.
Esketamine is a regulated prescription-only medication in Australia and may be considered for certain mental health conditions under the guidance of an appropriately qualified clinician. It is administered as a nasal spray under clinical supervision and may be considered an option for individuals experiencing treatment-resistant depression. Because Esketamine depression treatment differs in its mechanism of action from traditional antidepressants, it may be explored only after previous therapies have been trialled without sufficient response.
It is important to note that Esketamine therapy is not a first-line treatment. Instead, it is considered within a broader treatment plan, and only where a practitioner determines that it may be appropriate.
If a practitioner determines that Esketamine therapy may be appropriate, treatment generally follows a structured process that aligns with recognised clinical protocols. This allows the therapy to be administered safely and consistently.
Esketamine for treatment-resistant depression may be considered for adults who:
Every individual’s circumstances are unique. Eligibility for Esketamine depression treatment is determined through careful evaluation and open discussion between the individual and the treating clinician.
Esketamine is a Schedule 8 (controlled) medication and is administered within a highly regulated clinical framework. At Camberwell Specialists, we deliver treatment through a rigorously structured program that reflects the standards of a dedicated centre of excellence in neuromodulation and advanced psychiatric care.
All patients undergo a comprehensive specialist assessment to confirm suitability and ensure that treatment is clinically appropriate. Esketamine is administered exclusively on-site by experienced clinicians within a purpose-designed, medically supervised environment. Following each session, patients remain under close observation for a defined period to monitor physiological and psychological responses and to ensure safe recovery prior to discharge.
Care is overseen by a consultant psychiatrist, with ongoing review of treatment response, tolerability, and overall clinical progress. Standardised protocols guide every stage of care, including monitoring, documentation, and the management of side effects, ensuring consistency, safety, and clinical precision.
This model of care aligns with current regulatory requirements and is informed by contemporary evidence and best-practice guidelines for the use of esketamine in treatment-resistant depression.
Esketamine may be considered for some adults experiencing treatment-resistant depression, particularly where previous treatment approaches have not resulted in sufficient improvement. Suitability is determined through psychiatric assessment and review of treatment history.
Yes. A referral from a GP or psychiatrist is generally required before assessment for esketamine treatment can take place. The referral can be emailed to esketamine@tbsmelbourne.com.au
Yes. Esketamine is administered in a supervised clinical setting with monitoring before, during, and after treatment sessions.
Esketamine is commonly considered as part of a broader treatment plan that may include medication, psychological therapy, and ongoing psychiatric care.
Camberwell Specialists pride themselves on offering cutting-edge, evidence-based treatments tailored to each individual’s unique mental health challenges. From anxiety and depression to trauma and complex psychiatric disorders, our team uses proven therapeutic modalities like cognitive-behavioral therapy (CBT), psychodynamic therapy, and advanced interventions like rTMS and medication management to deliver the highest standard of care.
Our team consists of experienced psychologists, psychiatrists, and mental health specialists dedicated to your well-being. We combine clinical expertise with empathy to create a safe, supportive space where you can openly address your concerns and work towards meaningful growth. We prioritize building a strong therapeutic relationship, ensuring every patient feels heard, respected, and empowered throughout their journey.
At Camberwell Specialists, we understand that mental health needs vary widely. That’s why we provide personalized treatment plans tailored to your specific goals, preferences, and circumstances. Whether you require short-term support, long-term therapy, or innovative treatments, we collaborate with you to ensure the care you receive aligns with your needs, helping you achieve a healthier and more fulfilling life.
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